Testis-specific genes are essential for the spermatogenesis in mammalian male reproduction.A novel testis-specific/enriched gene, T672, was identified by hybridizing developmental st~ge of days 4, 9, 18, 35, 54 and 6 months of postnatalBalb/C mouse testis cDNA samples with Affymetrix Genechip.The scaling signal intensities of T672 in the six stages of mouse testis showed that the expression of 7672was not detected on day 4, 9 or 18 but on day 35, 54 and 6 months.And this developmental expression was further confirmed by RT-PCR.The full cDNA length of human T672 was 755 bp, with a 681 bp open reading frame encoding a 226 amino acids protein that was 81.1 % identical to a human homologue.RT-PCR analysis of T672mRN,A from multiple mouse and human tissues indicated the expression of T672 specifically or enriched in the testis.