Graphene is considered the ultimate material for applications in many fields, from electronics to composites and biosensors. Biological studies on graphene and graphene oxide are also currently underway in many laboratories. Large amounts of exfoliated graphene are therefore necessary for solution studies and applications in water and organic solvents. Graphene is usually prepared by the well known scotch tape technique or by CVD. As such, graphene cannot be dispersed in water or biological media, owing to its complete insolubility. Novel ways to prepare dispersible graphene in water are very much needed. Ball milling of graphite in the presence of melamine, developed in our labs, has proven a method of choice to exfoliate graphite and generate dispersions of few-layer graphene in many solvents, including water.