梗阻及非梗阻性无精子症患者睾丸支持细胞形态、拉曼光谱及表型差异

来源 :中华医学会第七次全国生殖医学学术会议 | 被引量 : 0次 | 上传用户：huoniao10

【摘要】

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【作者】

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马猛刘锋何琳刘阳杨浩李铮何祖平杨施张桢珍李朋公跃华刘林红朱勇田汝辉刘宇飞

【机构】

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上海交通大学附属仁济医院泌尿外科,上海市人类精子库,上海生殖医学重点实验室上海交通大学分析测试中

【出处】

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中华医学会第七次全国生殖医学学术会议

【发表日期】

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2013年7期

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论文部分内容阅读

背景非梗阻性无精子症(Non-obstructive azoospermia,NOA)占男性不育的10％,占无精子症患者的60％.唯支持细胞综合征(Sertoli cell-only syndrome,SCOS)是NOA中最严重的一种病理类型.目前NOA的发病机制还不清楚,支持细胞(Sertoli cell)是精子发生过程中最重要的体细胞,为精子发生提供了重要的微环境(niche).本研究旨在探索梗阻性无精子症(obstructive azoospermia,OA)及NOA患者睾丸支持细胞的形态、拉曼光谱特征,并对其表型进行差异比较.资料与方法选取2012年1月至2013年1月在我院接受治疗的男性不育患者200例(100例OA患者,100例NOA患者),年龄22～35岁.

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梗阻及非梗阻性无精子症患者睾丸支持细胞形态、拉曼光谱及表型差异

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