IL-17A, but not IL-17F, is indispensable for airway vascular remodeling induced by exaggerated Th17

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:yangqun0215
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Rationale and Objective: Our previous study has depicted an essential role of Th17 cells in excessive mucus secretion and airway smooth muscle proliferation in a prolonged ovalbumin (OVA)-challenged C57BL/6 mouse model.However,the impact of Th 17 cells against vascular remodeling, another characteristic features of airway remodeling in asthma, remains elusive.In this paper, we made further study to explore this issue.
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