【摘 要】
：
Understanding genomic variation and detecting selection signatures in a genome under selection have been great challenges for a century.In mammalian ovary,activ
【机 构】
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DepartmentofGenetics,CollegeofLifeSciences,WuhanUniversity,Wuhan430072,P.R.China
【出 处】
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第三届“模式生物与人类健康”发育遗传学全国学术研讨会
论文部分内容阅读
Understanding genomic variation and detecting selection signatures in a genome under selection have been great challenges for a century.In mammalian ovary,activation,development/exhaustion of primordial follicles determines reproductive success,menopause/end of female reproductive life.However,molecular mechanisms underlying oogenesis,particularly under artificial selection,are largely unknown.We report that a proteome-wide scan for selection signatures in the genome over 9,000-years of artificial pressure on the ovary revealed a general picture of selection signatures in the genome,especially genomic variations through artificial selection were detected in promoter and intron regions.
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