CCR2 and GPR177 gene polymorphisms and osteoporosis in elderly men of Chinese Han population

来源 :中华医学会第十四次全国内科学学术会议、第九届全国呼吸道感染学术大会、第五届全国抗感染药物合理应用论坛暨2013年北京-香 | 被引量 : 0次 | 上传用户:wanglei880917
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Objective This study aimed to investigate the association of CCR2 and GPR177 polymorphisms with bone mineral density in elderly men of Chinese Han population.Methods BMD of the proximal femur (femoral neck, Wards triangle and trochanter) and lumbar spine L2-L4 were measured by the dual-energy X-ray absorptiometry instrument.Data were statistically analyzed.Genotypes of CCR2 and GPR177 polymorphisms were examined through PCR and direct sequencing in 166 elderly men of Fuzhou city, with their BMD measured using the same method.Genotype and allele gene frequency were subsequntially calculated.
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