【摘 要】
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We investigated the relationship between indoor air pollution and the risk of childhood acute leukemia (AL).A community-based case-control study was conduct
【机 构】
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Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University, 280 Sout
【出 处】
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第六届亚洲特大城市环境与公共健康论坛暨中国环境科学学会环境医学与健康分会2015年会
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We investigated the relationship between indoor air pollution and the risk of childhood acute leukemia (AL).A community-based case-control study was conducted in Shanghai between April 2011 and January 2014, 97 cases aged<15,diagnosed with AL and 148 controls matched for age, gender and residence were enrolled.Questionnaire data was obtained, and quantitative measurements of indoor air were taken with passive samplers and analyzed by GC/MS.Higher concentrations of chlorinated hydrocarbons were observed in cases than in controls and were significantly increased the risk of childhood AL (OR=2.42, 95%CI=1.11-5.31).For the individual components, higher concentrations of butyl alcohol (OR=1.82,95%CI=1.04-3.21) and 1,2-dichloroethane (OR=1.80, 95%CI=1.02-3.19) were observed to be associated with an increased risk of childhood AL.The increased AL risk among children with higher concentrations of pollutants in their bedrooms suggests that indoor air pollution may be associated with the risk of childhood AL.
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