【摘 要】
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Hepatic steatosis is strongly associated with insulin resistance and metabolic complications of obesity.However,the mechanisms underlying intrahepatic triglyceride (TG) accumulation and its relationsh
【机 构】
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Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine,Scottsdale, Arizon
【出 处】
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The 2016 International Conference on Lipid Metabolism and Bi
论文部分内容阅读
Hepatic steatosis is strongly associated with insulin resistance and metabolic complications of obesity.However,the mechanisms underlying intrahepatic triglyceride (TG) accumulation and its relationship to lipid-induced toxic metabolic effects (“lipotoxicity”) remain unclear.Protection against lipotoxicity clearly requires a carefully regulated balance between TG synthesis and hydrolysis.
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