G0/G1 Switch Gene 2 (G0S2) Is a Dual-Function Regulator of Hepatic Lipid Metabolism Downstream of Li

来源 :The 2016 International Conference on Lipid Metabolism and Bi | 被引量 : 0次 | 上传用户:chensiyao159
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  Hepatic steatosis is strongly associated with insulin resistance and metabolic complications of obesity.However,the mechanisms underlying intrahepatic triglyceride (TG) accumulation and its relationship to lipid-induced toxic metabolic effects (“lipotoxicity”) remain unclear.Protection against lipotoxicity clearly requires a carefully regulated balance between TG synthesis and hydrolysis.
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