Genome-wide analysis of YB-1-RNA interactions reveals a novel role of YB-1 in miRNA processing in gl

来源 :第十一次全国基因功能与表观遗传调控学术研讨会 | 被引量 : 0次 | 上传用户:tony_zq
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Altered miRNA expression is believed to play a crucial role in a variety of human cancers;however,the mechanisms leading to the dysregulation of miRNA expression remain elusive.
其他文献
Vigilin, a multi-KH-domain protein, participates in heterochromatin formation.CCCTC-binding factor (CTCF) has been implicated in numerous aspects of chromosome
会议
  The Mediator complex orchestrates multiple transcription factors with the Pol Ⅱ apparatus for precise transcriptional control.However, its interplay with t
Glucose metabolic reprogramming is a hallmark of cancer.Cancer cells rapidly adjust their energy source from oxidative phosphorylation to glycolytic metabolism
会议
Objective—Endothelial cells (ECs) form blood vessels through angiogenesis, and participate in maintaining tissue homeostasis by cell fate change through endoth
会议
Nuclear speckles are dynamic nuclear domains located in interchromatin regions of nucleoplasm of mammalian cells.
会议
Pseudouridine is the most abundant post-transcriptional RNA modification.Although pseudouridine is well established in non-coding RNAs, little is known about it
会议
The pentatricopeptide repeat (PPR) proteins are a large family of RNA-binding proteins characterized by tandem repeats of a degenerate 35-amino-acid motif.
会议
食管癌是最常见的恶性肿瘤之一,严重威胁人们的生命健康.食管癌发生发展过程中的驱动基因及其致癌机制尚不明确,制约了食管癌分子标志物和靶向药物的发展.我们的研究发现CPT1
会议
  环状RNA(circularRNA,circRNA)是广泛存在于各种生物细胞中一类区别于传统线性RNA的新型形式,富集在胞浆中具有牢固的环状结构,大量存在于真核转录组中.大部分环状RNA是
Short hairpin RNAs (shRNAs) are widely used to produce small interfering RNAs (siRNAs) for gene silencing.
会议