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A new sesquiterpene, △9(10)-eremophilene-11, 12, 13-triol (1), a new oxazole, 4-(2-hydroxyethyl)-5-methyloxazole (2) and two known lactone 5-hydroxy-altemariol (3), alternariol (4) were isolated from the extract of Phomopsis sp.A240, an endophytic fungus isolated from the bark of Taxus chinensis var.mairei.The structures of isolated compounds were determined by extensive analysis of their spectroscopic data as well as by comparison with literature reports.The isolated compounds were evaluated for their cytotoxic and antioxidant activities.