论文部分内容阅读
Aims :A major factor contributing to failure of arteriovenous fistulas (AVFs) is migration of smooth muscle cells into the forming neointima.The problem with identifying the origin of cells that constitute a neointima is the absence of animal models that can specifically label these "SMC precursors".To overcome this shortcoming, we studied Wntl-Cre transgenic mice to label and track neural crest cells and their derivatives.Our aim in the present experiments was to identify the origin of SMCs in neointima.