Biodegradable and cell laden polymer microgels acting as functional building blocks for microscale tissue engineering have potential application in the construction of complex structures like native organs and tissue [1,2].Thermal sensitive chitosan/β-glycerol phosphate allows cell encapsulation during gelation,however the gelation is slow and there is no way to achieve patterned hydrogels.To in situ encapsulate cells during gelation and to fabricate the chitosan microgel with on-demand patterns,UV crosslinkable and water soluble chitosan methacrylic amide (Chi-MA) was synthesized via N site specific acylation.