【摘 要】
：
Objective:To investigate the osteogenic potential of gene activated nanobone putty.Methods:Twenty-four Kunming mice were used in this experiment.The mice were divided into two groups randomly.The nano
【机 构】
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贵州省人民医院骨科,贵阳,550002,中国 华中科技大学同济医学院附属联合医院骨科,武汉,430
【出 处】
：
2007SICOT国际矫形外科学术会议(SICOT-SIROT SHANGHAI CONGRESS 2007)
论文部分内容阅读
Objective:To investigate the osteogenic potential of gene activated nanobone putty.Methods:Twenty-four Kunming mice were used in this experiment.The mice were divided into two groups randomly.The nanobone putty + hBMP2 plasmid was injected into the right thigh muscle pouches of the mice (experiment side).The nanobone putty + blank plasmid or nanobone putty was injected into the left thigh muscle pouches of the group 1 (control side 1) or group 2 (control side 2) respectively.The effects of ectopic bone formation were evaluated by radiography,histology,and molecular biology analysis in 2 and 4 weeks after operation.
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