【摘 要】
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Objective:To investigate the therapeutical efficacy of extracellular polysaccharide (EPS)from Candida parapsilosis on the candidiasis.Methods: Construct a murine model of vaginal candidiasis, then con
【机 构】
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Department of Immunology,School of Laboratory Medicine & Tropical Medicine,Hainan Medical University
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Objective:To investigate the therapeutical efficacy of extracellular polysaccharide (EPS)from Candida parapsilosis on the candidiasis.Methods: Construct a murine model of vaginal candidiasis, then continuous in funding 100 μl EPS of 20mg/L for seven days, then observing the douche smear with the microscope, counting colony count of mycetes capacity value in vagina douche and histopathology detection of vaginal tissue.Results: In EPS group there are only a few inflammatory cells (HE dyeing), little hypha, a few spores in vaginal mucosa (PAS dyeing), a low mycetes counting Colony in vagina douche and little hypha, a few spores in the douche smear.Conclusion: EPS from Candida parapsilosisin can inhibit mycelial growth and Sporogony of candida albicans in Mouse model, and has strikingly therapeutical efficacy on the candidiasis of the mouse.
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