【摘 要】
：
Stroke is the second leading cause of death in industrialized countries.Despite tremendous research effort there is still only one approved therapy for acut
【机 构】
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Department of Neurology University of Wuerzburg Germany
【出 处】
：
中国上海第七届国际新药发明科技年会
论文部分内容阅读
Stroke is the second leading cause of death in industrialized countries.Despite tremendous research effort there is still only one approved therapy for acute ischemic stroke that is thrombolysis using recombinant tissue plasminogen acticator (rt-PA).However,only a small number of patients are amenable to this treatment because application of rt-PA is restricted to the first 3h after stroke onset.Moreover,all substances used for the prevention of cerebral ischemia such as warfarin or acetyl salicyl acid (ASA) bear an increased risk of symptomatic bleeding.Thus,there is an unmet need for more effective and safer strategies to treat ischemic stroke.
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