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Objective:Study the experience of 100 cases on the management of extracorporeal circulation during open heart surgery in infants less than 8kg.Methods:This group of CHD infants,age between 42 days to 2 years old and weigh between 4kg to 8kg.They use membrane oxygenator of Metronic,Medos or.MAQUET.Priming volume is about 500 ~ 700ml,we use HTK cardioplegic solution for cardiac protection.