This presentation will discuss the research efforts by our group in trying to bridge homogeneous and heterogeneous catalysis through the use of supramolecular environments and porous materials as platforms for deploying homogeneous catalysts. Supramolecular assemblies are large soluble structures constructed from molecules rather than atoms as building blocks. As thermodynamically stable structures, the stability of these materials comes from marshalling multiple weak interactions in a highly reinforcing way. In this sense, supramolecular chemistry has the potential for bringing together cooperative catalytic sites, stabilizing potent reaction centers, and creating architectures that elicit reaction selectivity. Previous examples from our group include assemblies capable of catalyzing enantioselective oxidation reactions, enantioselective epoxide ring-opening, and acyl transfer reactions with applications in sensing.