IMPORTANCE OF RADIATION-INDUCED PREMATURE SENESCENCE IN RADIOTHERAPY

来源 :第三届亚洲辐射研究大会 | 被引量 : 0次 | 上传用户:xiaoliang668
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Cellular senescence is a physiological program of irreversible growth arrest that is considered to play an important role in tumor suppression.
其他文献
Radiotherapy and chemotherapy have been commonly used for the treatment of cancers,but a variety of side-effects due to the normal tissue damage can be caused.
We can classify the compounds that modulate radiation injuries to three categories with respect to the timing of administration: i.e.the compounds for 1) prophylaxis, 2) mitigation, and 3) treatment o
Objective: Nitroxyl compounds have been reported as potential radioprotection drugs.To develop new radioprotectors, a novel chiral nitroxyl compound R-1 was synthesised.
To clarify the biological effects of space environment, especially space radiations, a proposal of "Rad Gene" was performed as the first life science experiment with two human lymphoblastoid cell line
MicroRNA (miRNA) is small non-coding RNA, which plays a key role in cellular response to environmental stresses by regulating gene expression in post-transcription level.
Space environmental condition composed of micro gravity and space radiation, of which the dose is at least one hundred times more compared with that on the earth.
Though basic life science has been rapidly advanced in recent years, the most sciences are limited under the earth environment.
Highly energized ionizing radiation (HZE particles) is severely risky to long-term manned exploration into outer space.
It is well-established that radiation induces apparent G2/M arrest in tumor cells as revealed by flow cytometric (FCM) analysis using DNA intercalaters such as propidium iodide.
On November 1992, a radiation accident occurred in Xinzhou due to pick-up an unused 60Co source by a farmer.There were total 37 individuals exposed to irradiation during the accident.