Mitoguardin, a novel mitochondrial protein, regulates mitochondria dynamics and neuronal homeostasis

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:lkks06
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Mitochondria undergo frequent morphologic changes through fission and fusion.Mutations in several core mitochondial fission /fusion machinery cause severe neurodegenerative diseases, such as Charcot-Marie-Tooth subtype 2A and autosomal dominant optic atrophy.
其他文献
  In vitro studies using pluripotent stem cells provide an essential tool for understanding hard-tostudy in vivo developmental processes.Human iPSCs also hold
  本研究观察微小RNA-203(miR-203)对人表皮干细胞表型转化的影响,探讨其诱导表皮干细胞向汗腺细胞分化的可能性及机制。取包皮环切术后的人正常包皮组织采用胰酶消化法分离
  目的:探讨人骨形态发生蛋白9(Bone morphogenetic proteins 9,BMP9)在体内外诱导人脐带间充质干细胞成骨分化的作用研究.方法:设立Ad-BMP9处理组或Ad-GFP对照组感染hUC-MSC
  胚胎干细胞具有无限增殖、自我更新和分化的特性,可被诱导为机体几乎所有的细胞种类,为细胞的遗传操作和分化研究提供丰富的实验材料,其全能性一直是研究的热点。生物化学和
C.elegans RAB-10 functions in endocytic recycling in polarized cells, regulating basolateral cargo transport in the intestinal epithelia and postsynaptic cargo
会议
  In most eukaryotic cells, receptor-mediated endocytosis is mediated by constitutively budding of clathrin-coated pits (CCPs) at spatially randomized sites b
  UNC-13/Muncl 3s play a central function in synaptic vesicle priming through their MUN domains.However, it is unclear whether this function arises from the a
  Autophagy is an intracellular degradation process that delivers cytoplasmic components and organelles to the vacuole for nutrient recycling in plants.During
The intracellular transport is fundamental for cell morphogenesis and functioning.To elucidate this mechanism we have identified and characterized kinesin super
会议
  An effective endomembrane system in higher organisms involves compartmentalization of the cell into separated organelles with distinct functions.Different c