Access to Spirooxindoles via Catalytic Asymmetric Michael/Hemiketalization/Fridel-Crafts Reaction of

来源 :河南省化学会2016年学术年会 | 被引量 : 0次 | 上传用户:qq231582
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  Spirooxindoles derivatives are one of the most common skeletons found in natural products.[1] The synthesis of this kind of compounds has been long-standing challenge in organic chemistry,and considerable effort has been devoted to developing efficient and selective synthetic methods to access substituted spirooxindoles.
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Spirooxindoles are attractive heterocyclic skeletons with broad and promising activities in various therapeutic fields.[1] As this frameworks have existed in a variety of natural products and pharmace