论文部分内容阅读
目的:分析影响口腔鳞癌预后及复发的临床病理因素,为进行综合治疗及其预后评价提供临床依据。方法:对407例原发口腔鳞癌患者以病变部位、肿瘤厚度、临床T分期、区域淋巴结转移、治疗方式、手术方式、术后组织学分级等指标研究与口腔鳞癌术后及复发相关的因素。结果:口腔鳞癌术后的复发率与病变部位、肿瘤厚度、临床T分期、区域淋巴结转移及组织学分级等因素有关,诱导化疗联合手术的综合治疗可有效降低口腔鳞癌的复发率。结论:临床工作中,我们应综合分析各种临床病理因素,对与术后复发关系较为密切的因素进行仔细评估,制定出有效的预防措施,提高口腔鳞癌的手术治愈率及生存率,降低复发率。
Objective: To analyze the clinicopathological factors that influence the prognosis and recurrence of oral squamous cell carcinoma and provide the clinical evidence for comprehensive treatment and prognosis evaluation. Methods: 407 patients with primary oral squamous cell carcinoma of the oral squamous cell carcinoma of the patients with lesions, tumor thickness, clinical T staging, regional lymph node metastasis, treatment, surgical methods, postoperative histological grade and other indicators of oral squamous cell carcinoma and relapse factor. Results: The recurrence rate of oral squamous cell carcinoma was related to the location of lesion, tumor thickness, clinical T stage, regional lymph node metastasis and histological grading. The combination of induction chemotherapy and surgery can effectively reduce the recurrence rate of oral squamous cell carcinoma. Conclusion: In clinical work, we should comprehensively analyze various clinicopathological factors, carefully evaluate the factors that have a close relationship with postoperative recurrence, and formulate effective preventive measures to improve the surgical cure rate and survival rate of oral squamous cell carcinoma and reduce Recurrence rate.