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  5. Novel multifunctional “nano-eggs” for drug delivery to cancer cells and cancer stem cells based on p

Novel multifunctional “nano-eggs” for drug delivery to cancer cells and cancer stem cells based on p

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：SF20070601ZW126com
【摘 要】
：
In this study, we prepared a multifunctional oligosaccharides of hyaluronan (oHA) conjugates,oHA-histidine-menthone 1,2-glycerol ketal (oHM).The oHM conjugates possess pH-sensitive menthone 1,2-glycer
【作 者】
：
Daquan Chen Kaoxiang Sun Youxin Li ZimeiWu Wanhui Liu 
【机 构】
：
School of Pharmacy, Yantai University, Shandong Co-innovation Center of New Formulations and Biotech
【出 处】
：
2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会
【发表日期】
：
2015年9期
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　　In this study, we prepared a multifunctional oligosaccharides of hyaluronan (oHA) conjugates,oHA-histidine-menthone 1,2-glycerol ketal (oHM).The oHM conjugates possess pH-sensitive menthone 1,2-glycerol ketal (MGK) as hydrophobic moieties and oHA as the target of CD44 receptor.Anticancer drugs, curcumin(Cur) and paclitaxel(PTX), was loaded into oHM micelles via self-assembly.
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