Specific Binding to Fullerene C60 Nanocrystals Locks Hippocampal CaMKⅡ in an Active Conformation

来源 :2013全国生物与医学纳米技术博士生学术论坛 | 被引量 : 0次 | 上传用户：xianxing599

【摘要】

：

　　In a biological environment, nanoparticles encounter and interact with thousands of proteins, forming a protein corona on the surface of the nanoparticles,

【作者】

：

Jing Xu Longping Wen

【机构】

：

SchoolofLifeSciences,UnivrsityofScienceandTechnologyofChina

【出处】

：

2013全国生物与医学纳米技术博士生学术论坛

【发表日期】

：

2013年9期

【关键词】

：

Nano C60 CaMKⅡ interaction active conformation long term potentiation

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　　In a biological environment, nanoparticles encounter and interact with thousands of proteins, forming a protein corona on the surface of the nanoparticles, but these interactions are generally perceived as non-specific protein adsorption, with protein unfolding and deactivation as the most likely consequences.

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Specific Binding to Fullerene C60 Nanocrystals Locks Hippocampal CaMKⅡ in an Active Conformation

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