The Wind Tunnel Based Virtual Flight Testing (WTBVFT) could replicate the actual free flight and explore the aerodynamics/flight dynamics coupling mechanism during the maneuver in the wind tunnel.The basic WTBVFT concept is to mount the test model on a specialized support system which allows for the model freely rotational motion, and the aerodynamic loading and motion parameters are measured simultaneously during the model motion.The simulations of the 3-DOF pitching motion of a typical missile in the vertical plane are performed with the open-loop and closed-loop control methods.The objective is to analyze the effect of the main differences between the WTBVFT and the actual free flight, and study the simulation method for the WTBVFT.Preliminary simulation analyses have been conducted with positive results.These results indicate that the WTBVFT that uses closed-loop autopilot control method with the pitch angular rate feedback signal is able to replicate the actual free flight behavior within acceptable differences.