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Background Tomato allergy is frequently clinically manifested as urticaria and gastrointestinal symptoms.Three tomato allergens, Lyc e 1 (profilin), Lyc e 2 (invertase) and Lyc e 3 (nsLTP) are listed in the official IUIS allergen database.Sensitivity pattern of human sera derived from allergic specimen do show polysensitization against all allergens described.In contrast sera from carrot allergic patients mainly react against major carrot allergen Dau c 1 and its isoforms.