【摘 要】
：
活疗化疗免疫学检查分子生物学MRD的重要性白血病疗效的再提高—实现真正意义上的个性化治疗之前MRD已成为儿童ALL治疗中重要的评估指标—治疗中机体肿瘤细胞的负荷—间接提
【出 处】
：
2013年全国小儿血液与肿瘤学术会议
论文部分内容阅读
活疗化疗免疫学检查分子生物学MRD的重要性白血病疗效的再提高—实现真正意义上的个性化治疗之前MRD已成为儿童ALL治疗中重要的评估指标—治疗中机体肿瘤细胞的负荷—间接提供肿瘤细胞对药物等治疗反应信息由于免疫学、分子生物学的进展,在初诊ALL获得肿瘤标志物,采用多参数流式细胞术以及荧光定量PCR法对早期治疗后的MRD水平进行监测,它的敏感度是常规骨髓形态学的10倍,达到10-4或以上.
其他文献
Patients with COPD are limited by breathlessness and eventually develop ventilatory failure.The disease imposes an increased load on the respiratory system and
Disclaimer Klaus F.Rabe Have served on FDA and EMA panels for registration of drugs for COPD Have served on advisory panels for most pharmaceutical companies ma
Central sleep apnoea (CSA) can be divided into hypercapnic (due to hypoventilation disorders) and hypocapnic (due to hyperventilaton disorders).The hypocapnic t
T细胞急性淋巴细胞白血病(T-cell acute lymphoblastic leukaemia,T-ALL)占儿童期ALL的15％左右,指的是肿瘤细胞表达CD3,CD7,CD2,CD5等标志的ALL.T-ALL男孩较多,年龄较大,白细
In many parts of the world, the prevalence of obesity is increasing at an alarming rate.The association between obesity, multiple comorbidities and increased ri
Osteoarthritis (OA) is the most widespread chronic degenerative joint disorder, characterized by progressive destruction of articular cartilage, subchondral
While Chronic Obstructive Pulmonary Disease (COPD) is by aetiology a pulmonary condition, several observations suggest that skeletal muscle may be an attractive
主要内容儿童ALL的基因学分型血浆miRNA与ALL诊治预后未来研究展望儿童ALL的基因学分型儿童ALL的基因标志(2000)基因变异在ALL中的作用变异:ETV6-RUNX1 BCR-ABL1 MLL重排TCF3
This lecture focus on the scientific evidence and practical issues in treatment of OSA.Ⅰ.Treatment modalities:A.CPAP-1) CPAP models-many technological advances
分别在1990-1994,1995-1999,和2000-2005进入儿童肿瘤研究组(Childrens Oncology Group)患者的总生存率婴儿急淋特性*小于365天*占儿童急淋3-5％*60-70％有chromosome 11q23异变: