2. 您的位置
3. 首页
4. 会议论文
5. Preparation and evaluation of exenatide loaded PLGA nanocapsules for oral administration

Preparation and evaluation of exenatide loaded PLGA nanocapsules for oral administration

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：xinzhichaoniao

【摘 要】

：

Protein and peptide drugs are usually administered by injection,but the pain induced by the injection causes poor patients compliance,especially for long-term administration.Oral delivery system is ec

【作 者】

：

Tingyuan Yang Yuejia Qiu Jilei Jia Ting Lu Lianyan Wang Guanghui Ma 

【机 构】

：

State Key Laboratory of Biochemical Engineering,Institute of Process Engineering,Chinese Academy of

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

exenatide nanocapsules oral administration 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Protein and peptide drugs are usually administered by injection,but the pain induced by the injection causes poor patients compliance,especially for long-term administration.Oral delivery system is economic and simple with very good patient compliance.

其他文献

Targeted intracellular delivery of shikonin effectively induces osteosarcoma necroptosis with downwa

Osteosarcoma is one of the most common types of primary malignant bone tumors in children and adolescents.

会议

sarcoma targeting peptidepolypeptide nanogelintracellular drug deliverynecrop

Multifunctional thermo-sensitive liposomes for tumor-triggered targeting drug delivery

The ammonium bicarbonate (ABC) liposomes have shown to release doxorubicin (DOX) rapidly at elevated temperatures (40-42 ℃) and improve the intravenous stability at physiological temperature (37 ℃)[1]

会议

tumor-triggered targetingthermo-sensitiveliposomedrug delivery

Synthesis of phenylboronic ester-linked Y-shape polymer via passerini reaction for ROS-responsive dr

Recently,oxidation-responsive polymers have been demonstrated to be promising for various biomedical applications[1].Among them,polymers containing phenylboronic acid/ester have attracted much attenti

会议

passerini reactionphenylboronic estermicellesROSH2O2

Laponite-based nanohybrids for enhanced solubility of dexamethasone and osteogenic differentiation o

It has been shown that dexamethasone (Dex) can induce the osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro in the presence of glycerophosphate and ascorbic acid[1].

会议

dexamethasonelaponitemesenchymal stem cellsosteogenic differentiation

Microneedle arrays fabricated with two types of multifunctional liposomes as a vaginal mucosal vacci

To develop effective mucosal vaccines,two types of functional liposomes,the mannosylated lipid A-liposomes (MLLs) with a size of around 200 nm and the stealth lipid A-liposomes (SLLs) of 50 nm,both lo

会议

microneedlevaginal vaccinationlysosome escapecross presentationmucosal immun

Human monocyte-targeted non-viral siRNA delivery for the suppression of inflammatory macrophages

Antibodies have been applied for the development of targeted gene delivery systems.Single chain antibodies targeting Herceptin and EGFR delivered siRNAs to cancer cells specifically and suppressed tum

会议

monocyte targetingsingle chain antibodygene silencinginflammatory diseases

A facile preparation of edible SPI/CS hybrid microballoon and its controllable release behaviors

Proteins and polysaccharides are renewable,abundant and environmental friendly natural polymers which show biocompatibility and biodegradability.Therefore,some discarded or low-cost biopolymers have b

会议

isolated soy proteinhybrid microballoonsedible drug carrierchitosancontrolla

Enhanced antitumor effect of poly(L-glutamic acid)-rose bengal conjugate nanoparticle

Rose Bengal (4,5,6,7-tetrachloro-2,4,5,7-tetraiodofluorescein disodium,RB) can function as photosensitizer,which can initiate different pathways of cancer cell death including apoptosis,autophagy,and

会议

rose bengalphotodynamic therapypoly(L-glutamic acid)nanoparticle

Surface-initiated RAFT polymerization of pseudo-superhydrophilic polymer brush as intraocular lens c

The extract of cloudy lens and implantation of intraocular lens (IOL) is the only effective clinical treatment to cataracts.However,a common complication named after cataract,or posterior capsular opa

会议

intraocular lenssurfacemodificationSI-RAFTanti-adhesionpseudo-superhydrophi

Supramolecular hybrids of carbon dots with doxorubicin and their cellular trafficking

Supramolecular stacking of doxorubicin (Dox) on carbon-based nanomaterials for biomedical applications has been studied since the pioneering work by Liu et al.[1].Carbon dots (CDs),as a new kind of dr

会议

carbon dotsdoxorubicinsupramolecular hybridspolydopamine