【摘 要】
：
The information generated in DMPK studies is critical to the understanding the mechanism of drug metabolism and elimination in mammalian system.Whereas DMPK
【机 构】
：
Imperial College, London, UK
【出 处】
：
第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
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The information generated in DMPK studies is critical to the understanding the mechanism of drug metabolism and elimination in mammalian system.Whereas DMPK studies can be categorized as targeted analysis, metabonomics is a non-targeted, unbiased approach of analysis; which has been employed for monitoring the effects of drug toxicity and more recently desease state progression.The analytical information used in both of these types of studies has traditional been generated by a combination of LC, MS, UV, NMR and radio chemical detection.
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