Mycoplasma genitalium membrane lipoproteins induced HO-1 expression negatively regulates cytokines e

来源 :The 6th Meeting of the Asian Organization for Mycoplasmology | 被引量 : 0次 | 上传用户：zyqtc1989

【摘要】

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【作者】

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Xiaoxing You Yanhua Zeng Cuiming Zhu Ranhui Li Zhongliang Deng Xiaohua Ma Chuanhao Jiang Minjun Yu Yimou Wu

【机构】

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Institution of pathogenic biology, Medical College;Hunan Provincial Key Laboratory for Special patho

【出处】

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The 6th Meeting of the Asian Organization for Mycoplasmology

【发表日期】

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2014年7期

【关键词】

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Mycoplasma genitalium Membrane lipoproteins Heme oxygenase-1 Placental trophobla

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　　Objective The aim of this study was designate to observe the expression of heme oxygenase-1 (HO-1) in regulation of cytokines response induced by Mycoplasma genitalium-derived membrane lipoproteins in placental trophoblast cells.Methods Placental trophoblast cells were cultured in vitro and stimulated by different concentration of membrane lipoproteins, expression of HO-1 mRNA and protein, and nuclear translocation of NF-E2-related factor 2 (Nrf2) were detected by Real-time PCR and Western blot, respectively.

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