The toxic effects and possible mechanisms of trichosanthin (TCS) on cancer cells

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户:lmh860628
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Trichosanthin (TCS), a commonly used traditional Chinese medicine for early and mid-term abortion, has been found to belong to type Ⅰ ribosome-inactivating proteins.Additionally,TCS has been reported to inhibit cell growth of a variety of cancers, including cervical cancer, choriocarcinoma, and leukemia/lymphoma, etc.
其他文献
Ischemic cerebrovascular disease is one of the most common disease.Angiotensin converting enzyme inhibitor captopril is one of the antihypertensive drugs.To investigate effects of captopril on cerebra
会议
To investigate the therapeutic effect and mechanism of the TFHL on the focal cerebral ischemia rats.Male SD rats were randomly divided into sham group, model group, TFHL group and ginkgo-leaf group.Su
会议
Thioredoxin (Trx), a 12kDa protein, has different forms depending on the different environment and plays an important role in anti-oxidative, anti-apoptosis and regulating transcription factors.Advanc
会议
Diabetic retinopathy(DR) is one of the major complications of diabetes.Liraglutide is recognized as a new medicine for type 2 diabetes mellitus(T2DM).Our study aimed to investigate the pathogenesis of
会议
The biodegradable poly (ε-caprolactone)/poly (trimethylene-carbonate)has received considerable attention for tissue engineering.The major limitation of PCL/PTMC electrospun scaffold, however, is that
会议
Fluid shear stress (FSS) is the main physical force as primary stimuli for arteriogenesis.However the underlying mechanism remains unclear.MicroRNA (miRNA) is small noncoding RNA, acts as negative reg
会议
A novel hybrid hydrogel was prepared and investigated based on silkworm silk fibroin and poly N-isopropylacrylamide (PNIPAAm).PNIPAAm was introduced to silk fibroin and resultant composite hydrogel wa
会议
MLT(melatonin, MLT) is a small organic molecule produced mainly by the pineal gland.MLT exerts obvious oncostatic effects.Previously studies have demonstrated that MLT has the inhibitory action to the
会议
The aim of this study was to observe the behavior change and the expression of Bcl-2 and Bax in the hippocampus of rats after treated with single-prolonged stress.Wistar rats were divided randomly int
会议
A retrospective study of the profiles of pain patients admitted into pain clinics and hospitals is rare in China.This study was based on the electronic medical records of pain patients hospitalized in
会议