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  5. Design, synthesis and activity evalution of novel peptide fusion inhibitors targeting HIV-1 gp41

Design, synthesis and activity evalution of novel peptide fusion inhibitors targeting HIV-1 gp41

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：vitor330
【摘 要】
：
Background: Human immunodeficiency virus type 1 (HIV-1), which is the pathogen of acquired immunodeficiency syndrome (AIDS), causes about 2 millions death every year.Based on the carboxy-terminal hept
【作 者】
：
谭建军 苏敏 李春华 张小轶 王存新 
【机 构】
：
生命科学与生物工程学院,北京工业大学,北京,100124
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
Drug design HIV-1 Fusion inhibitor 
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　　Background: Human immunodeficiency virus type 1 (HIV-1), which is the pathogen of acquired immunodeficiency syndrome (AIDS), causes about 2 millions death every year.Based on the carboxy-terminal heptad repeat (CHR) region of the transmembrane subunit of envelope protein (gp41) of HIV, several fusion inhibitors have been discovered.
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