胃癌中NK细胞功能失调的机制研究

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：whoabc

【摘要】

：

背景:胃癌是全球排名第四的恶性肿瘤,免疫抑制微环境的建立与持续性存在是导致胃癌发生发展的重要因素,我们前期的研究发现胃癌中CD8+T细胞功能受到抑制并介导了胃癌的不断进展和预后不良,而作为另一重要的抗肿瘤免疫细胞即NK细胞在胃癌中的功能和调控并不清楚.目的:研究NK细胞在胃癌中的功能变化及其调控,进一步阐明胃癌免疫逃逸的机制.方法:流式细胞技术检测NK细胞在胃癌患者不同组织中的分布、表型及功能,流

【作者】

：

彭六生王婷婷陈娜李文华吕一品毛方圆程平庄园邹全明

【机构】

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重庆市第三军医大学药学系微生物与生化药学教研室

【出处】

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中国免疫学会第九届全国免疫学学术大会

【发表日期】

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2014年8期

【关键词】

：

胃癌 NK细胞进展

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胃癌中NK细胞功能失调的机制研究

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