Disulfide-Crosslinked Hyaluronic Acid Nanoparticles for CD44-Targeting and Active intracellular Drug

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户:wqh4975156
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The existence of multidrug resistance (MDR) poses a major barrier for the clinical treatment of various malignant human cancers, and the polymeric nanoparticles have been shown potential in overcoming MDR.However, the conventional polymeric nanoparticles are plagued by low stability, poor tumor cell uptake, as well as deficient drug release inside the target tumor cells.
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