A Human Tumor Genome Project: From Sequence to Structure, Function and Possibly Drug Targets

来源 :2013第六届世界癌症大会 | 被引量 : 0次 | 上传用户:ddeng
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  BAG-1 is an anti-apoptotic protein that interacts with a variety of cellular molecules to inhibit apoptosis.The mechanisms by which BAG-1 interacts with other proteins to inhibit apoptosis have been extensively explored.However, it is currently unknown how BAG-1 expression is regulated at the molecular level, especially in cancer cells.Here we reported to clone a novel down-regulated BAG-1 expression gene named FLJ20420 using hBAG-1 promoter as a probe to screen Human Hela 5 cDNA library by Southern western blot.
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