【摘 要】
:
Adult T-cell leukemia/lymphoma (ATLL) is a malignant lymphoproliferative disorder caused by human T-cell leukemia virus type 1 (HTLV-1).HTLV-1 is endemic in south-western Japan and the Caribbean basin
【机 构】
:
Department of Dermatology, University of Miyazaki Japan
论文部分内容阅读
Adult T-cell leukemia/lymphoma (ATLL) is a malignant lymphoproliferative disorder caused by human T-cell leukemia virus type 1 (HTLV-1).HTLV-1 is endemic in south-western Japan and the Caribbean basin.HTLV-l-induced ATLL has been divided in 4: hematological subtypes as acute,lymphoma, chronic, and smoldering.Chronic and smoldering ATLL have a relatively good prognosis,even without treatment.These types can, however, evolve to acute ATLL, which has a poor prognosis:the median survival time (MST) after ATLL diagnosis is only 6 months.Specific skin lesions are caused by infiltration of the skin by the tumor cells and have been described in about half of patients with ATLL.We previously studied 124 cases of ATLL with specific skin lesions.
其他文献
Humans frequently sacrifice resources to help others——even strangers.The proximate mechanisms inducing such sacrifices are not wellunderstood, and we hypothesized that touch might provoke a sacrifice
Alzheimers Disease (AD) is the most prevalent form of age-related dementia, which affects about 5% of individuals over the age of 65 and more than 20% over the age of 80.The analysis of contemporary a
Alzheimers disease (AD) is an aging-related neurodegenerative disease with no known etiology and no effective treatment.Accumulation of amyloid beta peptide (A) in the brain is a pathological hallmark
Skeletal muscle contractions during static hold tasks have significant oscillations in the beta frequency range (i.e., 15-35Hz).This local beta oscillation is synchronized with that in the sensorimoto
Microcephaly is a neurodevelopmental disorder causing significantly reduced cerebral cortex size.In this report we will describe two Israeli Arab families with several siblings with genetic microcepha
The current tobacco epidemic presents a major public health challenge globally and within Europe.The presentation will build upon the findings of the Public Health Work-stream of the 2nd European Work
A number of papers have been published using gene expressions as predictors of outcomes in cancer patients.This genomic information is expected to greatly improve prognostic capabilities.The papers ha
Breast cancer is the most prevalent and the leading cause of death from cancer in women worldwide.The low percentage of cases related to reproductive history risk factors and to genetics suggests that
It is estimated that all the currently known breast cancer susceptibility genes account for G)in the CD44 intronl region in 90% of breast cancer patients as well as additional novel polymorphisms in t
Devil Facial Tumour Disease (DFTD) is a unique clonal cancer that threatens the worlds largest carnivorous marsupial, the Tasmanian devil (Sarcophilus harrisii) with extinction.The cancer is transmitt