Transplantation of caspase-8 shRNA-modified mesenchymal stem cells improves infarcted heart function

来源 :中国病理生理学会心血管专业委员会第十五届学术大会暨国际心脏研究会中国分会第十二届学术大会 | 被引量 : 0次 | 上传用户:Stephanie1121
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AIM: The clinical efficacy of mesenchymal stem cells (MSCs) has been verified by several clinical trials, but the beneficial effects of MSCs are greatly limited due to poor survival after transplantation into ischemic hearts.Here we investigated whether caspase8 shRNA-modification enhance hMSCs survival and improve infarcted heart function.
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