Intraoperative monitoring of cerebral blood flow(CBF)is of interest to neuroscience researchers,which offers the assessment of hemodynamic responses throughout the process of neurosurgery and provides an early biomarker for surgical guidance.However,intraoperative CBF imaging has been challenging due to animals motion and position change during the surgery.In this paper,we presented a designof an operation bench integrated with laser speckle contrast imager which enables to monitor the CBF intraoperatively.With a specially designed stereotaxic frame and imager,we were able to monitor the CBF change in both hemispheres during the surgery of rodent.The rotatable design of the operation plate and implementation of online image registration allows the technician to move the animal without disturbing the CBF imaging during surgery.The performance of the system was tested by middle cerebral artery occlusion(MCAO)model of rats.