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5. Andrographolide inhibit isoproterenol-induced myocardial hypertrophy in rats by reducing the excessi

Andrographolide inhibit isoproterenol-induced myocardial hypertrophy in rats by reducing the excessi

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：lxwhuochai

【摘 要】

：

Aim: To explore the inhibition effect of andrographolide (AP) on myocardial hypertrophy induced by isoproterenol (Iso), and the mechanism about autophagy regulation.Methods: Myocardial hypertrophy ani

【作 者】

：

Xing-ming ZHONG Xue-liang ZENG Bei LI Xiao LI Zhi-hua HUANG Jing ZENG 

【机 构】

：

The First Affiliated Hospital, Gannan Medical University, Ganzhou 341000, China

【出 处】

：

The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

：

2013年4期

【关键词】

：

andrographolide isoproterenol cardiac hypertrophy autophagy 

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Aim: To explore the inhibition effect of andrographolide (AP) on myocardial hypertrophy induced by isoproterenol (Iso), and the mechanism about autophagy regulation.Methods: Myocardial hypertrophy animal model was induced in rats by subcutaneous injection of isoproterenol (1 mg/kg) for 10 consecutive days, once a day.

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