The role and mechanism of curcumin in the expression of NF-κB and CX3CR1 after chronic constrictive

来源 :中华医学会第22次全国麻醉学术年会 | 被引量 : 0次 | 上传用户:wanghuaifei
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Curcumin is derived from turmeric, the powdered rhizome of the medicinal plant Curcuma Ionga Linn.NF-KB regulates the transcription of many inflammatory mediators, and spinal cord NF-KB activation is involved in exaggerated pain states.1 CX3CR1, a chemokine reporter which is expressed by microglia, supports a potential role in the mechanisms that contribute to the exaggerated pain state.
其他文献
案例解析—病例介绍:患者女,69岁,"双膝疼痛十余年,加重伴活动受限2个月"为主诉入院.入院诊断:双膝骨性关节炎高血压病2级心脏起搏器植入术后拟行手术:左膝关节表面置换术术前主要检查血常规:Hb93g/L(↓)心电图:正常,未见起搏钉心彩超:高血压性心脏改变主动脉增宽左房左室增大左心室舒张功能减退
会议
Propofol, an emulsion formulation of 2,6 diisopropylphenol, which is rapid-action and short acting intravenous anesthetics, was applied to clinical for several decades ,the research on its interaction
Intraoperative hypothermia is common because of anesthetic-induced impairment of thermoregulatory control and exposure to a cool operating room environment.Although there are methods for preventing in
Despite recent advances in antibiotic therapy and intensive care, sepsis is still considered to be the most common cause of death in intensive care units (ICU).Recently, we have found that hydrogen ga
Penehyclindine (PHCD), a new compound which functions well as anticholinergic, has been proposed to reduce lung and lethal toxicity.The mechanisms responsible for the effects of Penehyclindine hydroch
Acute lung injury(ALI) has a high death rate reaching up to 30~40%,because of acute respiratory failure[1].Experimental evidence has documented the protective effect of hydroxyethyl starch(HES) 200/0.
How isoflurane modulate the cerebral function? One of the hypothesis is that it may influence the synchrony of neuronal networks as reflected by studies on rats 12.To verify this,we applied resting-st
会议
Background Transcranial electrical motor evoked potentials (TceMEPs) can reflect the integrity of the motor system pathways and provide early warning of possible motor compromise.There are few reports
会议
The continuous brachial plexus nerve block (BPNB) can provide effective pain relief for upper extremity surgery.1This prospective study was conducted to investigate the suitable concentration of sufen
Background Sevoflurane, one of the most commonly used inhalation anesthetics, induces apoptosis and oxidative stress upon lymphocytes;1 while propofol, an intravenous anesthetic,exhibits anti-apoptoti