【摘 要】
：
The fluorinated molecules have found increasing applications in different fields, such as medicinal and materials chemistry1.Due to the containing of "-CHF-S-" moiety, the α-fluoro-sulfides can be use
【机 构】
：
The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Scie
【出 处】
：
中国化学会第十届全国天然有机化学学术会议
论文部分内容阅读
The fluorinated molecules have found increasing applications in different fields, such as medicinal and materials chemistry1.Due to the containing of "-CHF-S-" moiety, the α-fluoro-sulfides can be used as fluoropeptidomimetics2, as well as used for the preparation of terminal vinyl fluorides by thermolysis of the corresponding fluoro-sulfoxides3, therefore, many fluoro-reagents were used for α-fluorination of sulfides.
其他文献
Five new alkaloids, daphnicyclidins M and N (1 and 2) and calyciphyllines Q-S (3-5), alon with four known ones, paxiphylline C (6), macropodumine B (7), macropodumine C (8) an daphnicyclidin A (9), we
Five new chemical entities, mycosphines E-I (1-5), along with two known compounds,mycosphine A (6) and mycosphine B (7), were isolated from a mangrove rhizosphere soil derived fungus, Scedosporium api
目的 研究南海深海沉积物来源真菌Penicillium sp.F00120的次级代谢产物及抗菌活性.方法 采用硅胶、Sephadex LH-20、制备薄层进行分离纯化,通过波谱分析(1H NMR和13C NMR)鉴定其结构,采用滤纸片琼脂扩散法测试化合物的抗菌活性.
This study is part of our drug discovery program to identify biologically active compounds from medicinal plants.Justicia procumbens L.(Acanthaceae) is a medicinal plant known as "Juechuang" in China.
崖县风车子(Combretum alfredii)为使君子科(Combretaceae)风车子属(Combretum)植物,该属植物主要分布于热带和亚热带地区,是使君子科中比较大的属之一,使君子科植物我国有6属约13种,分布于长江以南各省区,主要产于广西、云南及海南岛1.风车子属植物具有健胃、驱虫、消炎等功效,在亚洲的不同地区被当作民间药广泛用于治疗肝炎、痢疾、呼吸道感染甚至癌症.
The medicinal plant Dictamnus dasycarpus is widely distributed in Asia, the root bark of this plant has been used for treatment of various ailments such as skin inflammation, eczema, rubella,scabies,
The genus Excoecaria (Euphorbiaceae) comprises of nearly 40 species, distributed throughout tropical, Asia and northwest Australia.Seven species are found in China, of which E.cochinchinensis, E.agall
The nuclear factor-κB (NF-κB), a ubiquitously expressed proinflammatory transcription factor,plays a crucial role in cell growth, apoptosis and tumorigenesis, and it makes the NF-κB signaling pathway
OSW-1 is a cholestane glycoside isolated from the bulbs of Ornithogalum saundersiae, which has exhibited exceptionally potent cytotoxicities against various malignant tumor cells1-3.Recent studies hav
黄芪素(Baicalein)又名黄芩苷元,对多种疾病包括炎症、肿瘤、纤维化性疾病、心脑血管性疾病以及神经性疾病具有良好的防治作用1-2.由于黄芩素水溶性和脂溶性比较差,在一定程度上限制黄芩素的临床应用范围.因此,本文以黄芩素为先导化合物对其进行结构修饰,采用拼合原理将具有抗炎、镇痛活性药物布洛芬与黄芩素进行拼合,改善黄芩素的脂溶性,并提高黄芩素的抗炎活性,期望扩大黄芩素临床应用范围.