MICRORNA-133B REGULATES PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS INDUCED BY LOW SHEAR STRESS

来源 :19th Annual Scientific Meeting of the Institute of Cardiovas | 被引量 : 0次 | 上传用户：chouyez

【摘要】

：

Objectives: Shear stress, especially low shear stress (LowSS), plays a crucial role in vascular remodeling, which is a major component of many cardiovascular diseases.Our previous study revealed that

【作者】

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Y Han YY Ma L Wang L Wang ZL Jiang

【机构】

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Institute of Mechanobiology & Medical Engineering,Shanghai Jiao Tong University,China

【出处】

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19th Annual Scientific Meeting of the Institute of Cardiovas

【发表日期】

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2015年9期

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Objectives: Shear stress, especially low shear stress (LowSS), plays a crucial role in vascular remodeling, which is a major component of many cardiovascular diseases.Our previous study revealed that shear stress induces the secretion of insulin-like growth factor1 (IGF1) from endothelial cells (ECs) and then modulates vascular smooth muscle cells (VSMCs) via paracrine control.

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MICRORNA-133B REGULATES PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS INDUCED BY LOW SHEAR STRESS

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