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Objective: This study aimed to investigate the difference of abdominal skin temperature responses following moxibustion compared with stimulation method.Methods: Moxibustion was applied to the acupuncture points of CV4, CV6, and CV12.Thirty healthy men were randomly divided into two groups: one received a single moxibustion stimulation in the three locations (n=15) and the other received triple moxibustion stimulations in one location CV12 (n=15) for 30 min.