【摘 要】
:
After a tightly regulated developmental program in the thymus, "mature" single positive (SP) thymocytes leave the thymus and enter the periphery.These newly arrived recent thymic emigrants (RTEs) are
【机 构】
:
Peking University Health Science Center China
论文部分内容阅读
After a tightly regulated developmental program in the thymus, "mature" single positive (SP) thymocytes leave the thymus and enter the periphery.These newly arrived recent thymic emigrants (RTEs) are phenotypically and functionally immature, and will complete a dynamic maturation in the peripheral lymphoid organs before being licensed to be resident naive T cells.
其他文献
Many related researches are in processing to investigate MSC cell fate for genetic, epigenetic, cell cycle regulation, immune regulatory and microenvironment.Especially, disruption of epigenetic regul
HIV and SIV pathogenic infection is characterized by early CD4+ T cell dysfunction.Using a protocol of optimized in vitro anti-CD3/28 mediated expansion of enriched CD4+ T cells, we have been able to
Reputed experts, international organizations and leading biomedical journals warn that the greatest risk to human health comes in the form of antibiotic-resistant bacteria.World Health Organizaton dec
The herpes simplex virus (HSV-2) can be acquired through sexual activity and has the ability to establish latent infection in host cells.Infection occurs when virions come in contact with abraded skin
Autoimmune mechanisms are involved in the development of diabetes.Intra bone marrow-bone marrow transplantation (IBM-BMT) + thymus transplantation (TT) has been shown to reduce the incidence of graft
Two types of antibodies are being developed to target soluble IgE in the blood and membrane-bound IgE (mIgE) on IgE-expressing B lymphoblast and memory B cells, for treating allergy and asthma.An ordi
Osteoarthritis (OA) has traditionally been considered a degenerative joint disease often initiated by biomechanical injury and its link to the aging process.Progress in molecular biology in the past 2
In the past decade, we have learned that tolerance in organ transplantation is linked to the development and pets istence of regulatory T cells (Treg).Therapeutic administration of Tregs has proven ef
Comparison of lifetime prevalence suggests higher rates of major depression in the inflammatory bowel disease (IBD).IBDs are associated with an autonomic imbalance and up to 35% of patients with ulcer
Recent studies showed that polymorphisms in interleukin 28B (IL28B) gene were associated with chronic hepatitis B virus (HBV) infection in Chinese.However, there are still no any reports in associatio