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在肿瘤的临床治疗中,ABC家族转运蛋白介导的肿瘤多药耐药是恶性肿瘤患者化疗失败的主要原因.天然化合物结构新颖、种类繁多,从中寻找和开发高效、低毒的新型耐药逆转剂药物先导物是目前肿瘤多药耐药逆转剂研究的热点1.
菠萝蜜烷型三萜化合物升麻醇逆转肿瘤多药耐药作用及机制研究
【摘 要】
：
在肿瘤的临床治疗中,ABC家族转运蛋白介导的肿瘤多药耐药是恶性肿瘤患者化疗失败的主要原因.天然化合物结构新颖、种类繁多,从中寻找和开发高效、低毒的新型耐药逆转剂药物先导物是目前肿瘤多药耐药逆转剂研究的热点1.
【机 构】
：
暨南大学中药及天然药物研究所,广州,510632 暨南大学中药药效物质基础及创新药物研究广东省高校
【出 处】
：
中国化学会第十届全国天然有机化学学术会议
【发表日期】
：
2014年11期
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