论文部分内容阅读
Urinary organic acids,plasma amino acids and acylcarnitine profile analyses are used to diagnose inborn errors of metabolisms (IEM) when patients are in acute episode.But when patients are in remission,urine acylglycines are more useful as they are consistently raised.A liquid chromatography-electrospray ionizationtandem mass spectrometry (LC-ESI-MS/MS) method for the determination of urine acylglycines is set-up and local reference intervals are established.