人工诱发整夜反复微觉醒对心血管系统的影响研究

来源 :中华医学会第四届全国睡眠呼吸疾病学术会议 | 被引量 : 0次 | 上传用户:wxj1234567
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目的 探讨OSAS患者中反复微觉醒对心血管系统的独立影响方法 每个受试者接受连续两个晚上的睡眠监测,第一晚为对照夜,第二晚为实验夜,即通过一定间隔(约60次/小时)的音频信号刺激诱发受试者反复觉醒.对照夜及实验夜睡眠前后受试者均采集血压、心率变异指数及动脉硬度指数等生理指标及一氧化氮、内皮素-1、CRP、IL-6、TNF-a及VEGF等血清指标并将对照夜和实验夜的变化进行比较.
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