随着超分子化学研究的不断深入,纳米超分子组装体在许多领域展现出新的用途.众多的研究发现,药物分子作为客体分子与超分子主体,尤其是大环化合物,发生包结配位后,能够提高药物的稳定性,改善药物的水溶性,调节药物的释放速度,提升药物的生物利用度和疗效,改善药物的药代动力学性质,改进药物的剂型,掩盖药物的不良气味和降低刺激性及毒副作用.
Many biological important processes are related to the conformation andassembly state of specific gene,involved proteins and enzymes.Here wesummarize our recent research progress in this field [1-12].
烟酰胺腺嘌呤二核苷酸(NAD)及其还原态NADH是生命过程中的重要辅酶,参与生命体中一系列重要的生物化学过程。任何改变NAD浓度及其氧化还原状态的操作都会对细胞产生全局性影响,很难在辅酶水平对生物体系中特定的氧化还原酶进行控制。
Protein self-assembly into exquisite,complicated yet high-ordered architectures represents the supreme wisdom of nature.However,precisely manipulating protein self-assembling behaviors in vitro is a g
Background: Our goal is to identify specific markers on the endothelial surface of human brain arteriovenous malformations(AVMs)induced by ionizing radiation that could be used as targets to site-spec
Riboflavin(vitamin B2)has been thought to be a promising antitumoral agent in photodynamic therapy,though the further application of the method was limited by the unclear molecular mechanism.G-T misma
近年来,点阵夹芯结构凭借其高比强度、高比刚度等良好力学特性以及隔热、降噪等其它功能性特性,越来越受到航空航天工业的青睐。针对三维轻质点阵夹芯结构,因其比二维点阵夹芯结构复杂,对其力学问题的研究受到了学者们的广泛关注。
本文主要研究了带初始几何缺陷的功能梯度固支圆柱壳在不同体积分数下的非线性动力学行为。假设该材料的组分是沿厚度方向是呈梯度变化的,并且材料的属性是与温度相关的,受到横向载荷和面内激励的联合作用。
The Adenosine triphosphate(ATP),released from astrocytes,has been demonstrated to be critical for the propagating of the calcium wave in astrocyte network.This ATP-induced calcium wave has been define
The intensity and spectra feature of the noise and vibration sources on-board an underwater vehicle must be controlled in order to provide the submarine with a stealth capability to perform many of it