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Biological synthesis of nanoparticles is best source to avoid exposure of hazardous materials during chemical manufacturing of nanoparticles which is a severe threat towards biodiversity and environment.In this study, we are going to report detail bioreducing mechanism of silver nanoparticles formation and antiradiation activity in SHY5Y cell by using 50% ethanol extract of Dragons blood, a famous Chinese herbal plant.Color change during silver nanoparticles synthesis was observed and it was confirmed by Ultra violet (UV) visible spectroscopy having wave length at 430 nm after 30 min of reaction at 60 ℃.Well-dispersed silver nanoparticles with an approximate size (4 nm to 50 nm) were measured by TEM.