【摘 要】
：
Background, Motivation and Objective Non-invasive transdermal delivery of drugs offers a number of advantages over conventional delivery methods. For the past twenty years considerable attention was p
【机 构】
：
Guided Therapy Systems, Mesa, AZ, USA Ardent Soun
论文部分内容阅读
Background, Motivation and Objective Non-invasive transdermal delivery of drugs offers a number of advantages over conventional delivery methods. For the past twenty years considerable attention was paid to ultrasound assisted delivery at relatively low frequency (20 KHz-3 MHz) and low acoustic intensity (＜3w/cm2) requiring minutes to several hours to enhance delivery. The purported mechanism of action is associated with cavitation increasing drug diffusion through the stratum corneum and epidermis.
其他文献
Background, Motivation and Objective ScAlN has been attracted as a potential piezoelectric material for BAW and SAW resonators. The kt 2 of the ScAlN film near the phase boundary was approximately 200
Background, Motivation and Objective Photoacoustic (PA) imaging has been used for numerous applications in clinical medicine and preclinical studies. Usually, nanosecond laser pulses in the visible an
Background, Motivation and Objective Previous studies performed in our lab in a mouse model of cancer have shown that microbubble-mediated ultrasound therapy (MB-US) can enhance the accumulation of na
Background, Motivation and Objective Functionalised nanoparticles (NP) have been shown to enable delivery of small silencing RNA molecules (siRNA) to cancer cells, disabling proliferation and providin
Background, Motivation and Objective Ultrasound contrast agents (UCAs) have been recently studied for drug delivery applications, since cavitation can increase the temporary permeability of nearby cel
Background, Motivation and Objective The purpose of this work was to investigate whether low frequency, low intensity (LFLI, 20 kHz, ＜100 mW/cm2, spatial peak, temporal peak) ultrasound (US), delivere
Background, Motivation and Objective Focused ultrasound (FUS) combined with microbubbles is an attractive method to deliver therapeutic agents to brain tissue noninvasively, transiently and locally. R
Background, Motivation and Objective Drug addiction is a chronic disease of brain, which has a trend to recur. Animal experiments showed that gliacyte derived neurotrophic factor (GDNF) had an ideal t
Background, Motivation and Objective A quantitative diagnostic method for liver fibrosis using ultrasound echo signal is highly required. A probability density function (PDF) of echo amplitudes from a
Background, Motivation and Objective Thyroid cancer management is a complicated clinical problem due to the high prevalence of thyroid nodules in the general population and the relatively low prevalen