【摘 要】
：
Background, Motivation and Objective The purpose of this work was to investigate whether low frequency, low intensity (LFLI, 20 kHz, ＜100 mW/cm2, spatial peak, temporal peak) ultrasound (US), delivere
【机 构】
：
Hebrew University Jerusalem, Israel Drexel Univer
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Background, Motivation and Objective The purpose of this work was to investigate whether low frequency, low intensity (LFLI, 20 kHz, ＜100 mW/cm2, spatial peak, temporal peak) ultrasound (US), delivered by a light-weight (＜100g), tether-free, fully wearable, battery powered applicator has a potential as a tool for noninvasive, transdermal drug delivery. Such delivery is of interest because oral intake of a variety of drugs might be impeded due to side-effects such as decreased white blood cell counts, increased risk of infections, fatigue, oral ulcers, hair loss, nausea, and diarrhea, and liver toxicity.
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